The basal ganglia are a hub of interconnected nuclei embedded in an extensive brain-wide network, controlling movement, mood states, and higher brain functions.
Their selection-suppression operations serve as a paradigm in computational biology and neurorobotics.
Basal ganglia dysfunction causes neuropsychiatric disturbances and movement disorders.
The basal ganglia are evolutionarily conserved; vertebrate models of basal ganglia disease are translationally valid.
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